Journal of Bioanalysis & Biomedicine

Investigation of Correlation between Neurological Diseases and Breath Hexanal

Abstract

H Akman*, I Bayrakli and S Kutluhan

Breath analysis is a method that has the potential to be used as a non-invasive method for the diagnosis of diseases, in the planning of drug use, and in indicating the health status of the patient, and of which importance increases with each passing day. The aim of this study is to examine neurological diseases from breath hexanal. In our study, the breaths of a total of 29 individuals consisting of 9 multiple sclerosis patients, 8 Parkinson’s patients and 12 healthy individuals in the control group were examined by means of the thermal desorption gas chromatography mass spectroscopy method. According to the results obtained, hexanal molecule, known as the biomarker for lipid peroxidation, was observed in patients with a statistically significant difference compared to the control group with multiple sclerosis patients as p=0.048. No correlation was found between Parkinson’s patient and the control group.