Journal of Cancer Clinical Trials

Dubious Action of Atrazine as an Endocrine Disrupting Agent: An In silico Approach

Abstract

Shailima Rampogu, R.D. Neelima Vardhani, SSNP Ekke and Rajesh Goud Gajula

Atrazine is chlorine containing chemical compound which is widely used as an herbicide. However, upon its entry into the human body, it is known to affect several organs and their functions. Additionally, atrazine also represses photosynthesis in plants and causes serious disorders in animals as well. One of the most challenging actions of atrazine is its action has an endocrine disruptor. The present article makes an effort to delineate on the binding affinity of the herbicide to two human hormone receptors, and also to understand its endocrine disrupting capability adapting the computational methods.