Bioceramics Development and Applications

ISSN: 2090-5025

Open Access

Comparison of Two Composites Developed to be Used as Bone Replacement – PMMA/Bioglass 45S5® Microfiber and PMMA/Hydroxyapatite


Lourdes Cristina de Albuquerque Haach, Benedito de Moraes Purquerio, Nelson Ferreira Silva Jr, Ana Maria Minarelli Gaspar and Carlos Alberto Fortulan

Two types of polymer matrix composites were designed to use as bone replacement: PMMA+HA and PMMA+45S5® Blown Fibers. The materials were tested in vivo for 60 days and compared to two control groups: empty bone defect and porous PMMA. The histology results suggest that both materials provide a suitable scaffold for bone growth with the presence of newly formed bone tissue, blood vessels, osteocytes and osteoblasts cells. For a better understanding of the mechanical properties of scaffolds to bear physiological loads when implanted, compressive tests were carried out. The results showed difference in the compressive behaviour of the two composites, PMMA+HA specimens achieved higher values approaching 9.0 MPa of ultimate strength while PMMA+45S5® had values close to 8.0MPa. Both materials are suitable to bone replacement of small size areas.


Share this article

Google Scholar citation report
Citations: 1050

Bioceramics Development and Applications received 1050 citations as per Google Scholar report

Indexed In

arrow_upward arrow_upward