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The Impact Of Diabetes On TB | Open Access Journals
Journal of Diabetic Complications & Medicine

Journal of Diabetic Complications & Medicine

ISSN: 2475-3211

Open Access

The Impact Of Diabetes On TB

The global increase in type 2 diabetes mellitus (DM) is a recognized risk and re-emergence challenge for the fight against tuberculosis (TB). People with MD are three times more likely to develop TB and there are now more people with TB-DM co-morbidity than TB-HIV co-infection. The association between DM and TB was first described centuries ago by Avincenna, a Persian philosopher, and comorbidity was a frequent subject in the medical literature of the first half of the 20th century. (4-7) But this literature has decreased the car association has reduced awareness with insulin for diabetic patients and antibiotics for tuberculosis. In the 1980s, publications on joint MD-TB began to reappear in tandem with the MD `` pandemic '': the global prevalence of MD in adults has increased by 20% in less than 30 years, and the MD is expected to reach 642 million worldwide by 2040, most (80%) of patients living in low- and middle-income countries where tuberculosis is also endemic. (9) Therefore, the World Health Organization has identified MD as a neglected, significant and re-emerging risk factor for tuberculosis. In this chapter, “MD” will mainly refer to type 2 MD as it is the most common form, but type 1 MD in children has also been associated with tuberculosis. This chapter describes the epidemiology of MD-TB, the impact of MD on the clinical presentation and outcomes of TB, the underlying biology that promotes the co-occurrence of the two diseases, and the public health implications for tuberculosis control and MD management.

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