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Pulmonary TB Among Diabetic Patients | Open Access Journals
Journal of Diabetic Complications & Medicine

Journal of Diabetic Complications & Medicine

ISSN: 2475-3211

Open Access

Pulmonary TB Among Diabetic Patients

The link between diabetes mellitus and tuberculosis has been recognized for centuries. In recent decades, the incidence of tuberculosis has declined in high-income countries, but the incidence remains high in countries with high rates of HIV infection, high prevalence of malnutrition and conditions overcrowded, or poor TB infrastructure. At the same time, the prevalence of diabetes mellitus is skyrocketing globally, fueled by obesity. There is growing evidence that diabetes mellitus is an important risk factor for tuberculosis and may affect presentation and response to treatment. In addition, tuberculosis could induce glucose intolerance and worsen glycemic control in people with diabetes. We review the epidemiology of the tuberculosis and diabetes epidemics and provide a summary of the evidence for the role of diabetes mellitus in the sensitivity, clinical presentation and response to treatment of tuberculosis. In addition, we are examining the potential mechanisms by which diabetes mellitus can cause tuberculosis, the effects of tuberculosis on diabetes control, and pharmacokinetic issues related to the co-management of diabetes and tuberculosis.

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