Cancer Science & Therapy

Department of Pharmaceutical Sciences, Gurukula Kangri, Deemed to be University, Haridwar-249404, India

Publications

• Mini Review   
  Bartogenic Acid: A Promising Penatacyclic Triterpenoid in Cancer Research and Possible Mechanism
  Author(s): Satyendra Kumar Rajput*, Vishal Kumar Dubey, Shalini Singh and Swati Madan
  
  Bartogenic Acid (BA) is a natural triterpenoid compound found in several plants, including Barleria lupulina, Croton tiglium, and Euphorbia hirta. It has been shown to exhibit a wide range of pharmacological activities, including anti-inflammatory, anti-cancer and anti-oxidant properties. BA has been shown to exhibit promising anti-cancer properties in various studies. In particular, BA is effective against a variety of cancer cell lines, including breast, lung, and colon cancer. Its ability to induce apoptosis, inhibit cell proliferation, and suppress tumor angiogenesis makes it a potential therapeutic agent for various cancers. BA has been demonstrated to induce apoptosis in cancer cells through various mechanisms, including activation of the caspase cascade, downregulation of Bcl-2, and upregulation of Bax. It also inhibits cell proliferation by arresting cell cyc.. Read More»
  DOI: 10.37421/1948-5956.2024.16.626

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