Journal of Diabetic Complications & Medicine

ISSN: 2475-3211

Open Access

Kilari Eswar Kumar

Department of Pharmacology Division, Andhra University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, India

  • Research Article   
    Protective Effect of Feronia limonia for Diabetic Cataract and Retinopathy in Streptozotocin Induced Diabetic Rats
    Author(s): Putta Swathi and Kilari Eswar Kumar*

    The study evaluates influence of methanolic peel extract of Feronia limonia (MPFL) for antihyperglycemic activity, in vivo antioxidant Feronia limonia and its role in inhibiting the polyol pathway and formation of advanced glycation end products during diabetes induced cataract and Feronia limonia retinopathy. Diabetes was induced with 55 mg/kg of Streptozotocin (i.p) and was treated with MPFL 150 mg/kg and 300 mg/kg (p.o) once Feronia limonia daily for a period of 12 weeks. Blood glucose levels were estimated at the end of every 4 weeks. Serum was collected by retroorbitol plexus for Feronia limonia the estimation of protein carbonyls and advanced glycation end products. All the animals were sacrificed and separate the lenses for the Feronia limonia estimation of protein, superoxide dismutase, catalase, reduced glutathion.. Read More»

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