Journal of Clinical Case Reports

ISSN: 2165-7920

Open Access

Kanak Parmar

Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th St, Lubbock, TX, 79430-0002, USA

  • Case Report   
    A Possible Case of Acquired Hemophilia Following COVID−19 Vaccination
    Author(s): Kanak Parmar*, Shivam Singh, Robert Horn and Udit Verma

    COVID-19 vaccination has been very efficient in preventing severe illness and death from SARS CoV-2. These vaccines are usually reported to have mild and transient side effects. We report a case of a 59-year-old woman with an acquired hemophilia A following the administration of her second dose of mRNA 1273 vaccine. The patient presented with worsening swelling and bruising of her left arm three days after vaccination. She had a history of COVID-19 infection 3 months ago. Laboratory workup showed elevated partial thromboplastin time (PTT) and mixing study showed possible inhibitor. Factor VIII level (%) was <5% and the inhibitor panel confirmed presence of inhibitor. The patient was treated with high dose steroids and cyclophosphamide. Currently the patient is on slow taper steroids and hematoma has improved... Read More»
    DOI: 10.37421/2165-7920.2022.12.1543

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