Journal of Clinical Case Reports

Department of Plastic Surgeon, New York University, New York, United States

Publications

• Case Report   
  The Limits Of Diagnosis
  Author(s): Joshua Greenwald*
  
  Extraskeletal Myxoid Chondrosarcoma (EMC) is a rare Soft Tissue Sarcoma (STS) highly correlated with the NR4A3 gene rearrangement. This gene rearrangement has not been found in other tumors. However, its function is not yet fully known in cancer biology. Multiple prospective cohort studies show the population frequency of EMC as approximately 0.0001%. Cases of primary skeletal EMC’s have been reported, but the NR4A3 gene rearrangement is less correlated with it as compared to the soft tissue variant. EMC's tend to arise in the soft tissue of the proximal lower extremities and limb girdle in the fifth to sixth decade of life with a male predominance. Cases of EMC arising in the peripheral extremities are rarer still. And pathologic fractures secondary to chondrosarcoma’s are also highly unusual. The following patient presents with a primary tumour sh.. Read More»
  DOI: 10.37421/2165-7920.2022.12.1534

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