Journal of Phylogenetics & Evolutionary Biology

Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States

Publications

• Research Article   
  Continued Co-circulation and Evolution of the Ancient Subcontinent Lineage Despite Predominance of the Arctic-Like Lineage Rabies Viruses (RABV) in India
  Author(s): Jagadeeswaran Deventhiran, Bhuvaneswari Srinivasan, Manoharan Seeralan, Vijayarani Kanagaraj, Sangeetha Raju, Kumanan Kathaperumal, Ruth Nissly, Sunitha Manjari Kasibhatla, Mohan M Kale, Urmila Kulkarni-Kale and Suresh V Kuchipudi*
  
  Rabies is an emerging and re-emerging lethal viral encephalitis causing 26,400 to 61,000 human deaths annually. Domestic dog continues to be the key reservoir of rabies in endemic countries and almost all the human rabies deaths are attributed to dog bite. With regular interspecies transmission events of Rabies Viruses (RABVs) from dogs to humans, ~36% of the world’s rabies deaths occur in India that accounts to 20,000 fatalities due to rabies every year. Rabies is endemic among domestic dogs and due to sustained dog to human transmission it is conceivable that RABVs in India continue to evolve. Further, regular movement of people and animals between southern coastal states of India and Sri Lanka was proposed to be a source of the emergence of variant RABV in India. Hence it is essential to characterize the genetic diversity and evolutionary dynamics of RABV currently circulatin.. Read More»
  

  Abstract PDF