Journal of Oncology Translational Research

Leptin resistance is a complex physiological condition characterized by reduced sensitivity to the hormone leptin, which plays a crucial role in regulating appetite and energy expenditure. This resistance can lead to disruptions in normal body weight regulation, potentially contributing to obesity and related metabolic disorders. This abstract provides an overview of leptin resistance, its underlying mechanisms, and its implications for human health. Understanding leptin resistance is essential for addressing the global obesity epidemic and developing effective therapeutic strategies.

Cancer is a complex disease characterized by uncontrolled cell growth and proliferation. Over the years, extensive research has shed light on the intricate interplay of genetic and epigenetic factors contributing to cancer development. Understanding the roles of genetics and epigenetics in cancer is crucial for devising effective diagnostic and therapeutic strategies. This article explores the fundamentals of genetics and epigenetics in the context of cancer, highlighting their pivotal roles as key drivers of oncogenesis.

Cancer remains one of the most challenging health concerns worldwide, with its complexity spanning across multiple dimensions, including genetic and epigenetic factors. While significant strides have been made in understanding the genetic basis of cancer, the role of epigenetics, particularly the cancer epigenome, has gained prominence in recent years. The cancer epigenome refers to alterations in the epigenetic landscape of cancer cells, which play a crucial role in driving tumorigenesis and disease progression. In this article, we delve into the intricate world of the cancer epigenome, exploring its mechanisms and the insights it offers into cancer biology.

Chemotherapy has long been a cornerstone in the fight against cancer. However, its effectiveness can vary widely from patient to patient, with side effects often proving debilitating. In recent years, there has been a significant push towards tailoring chemotherapy treatments to individual patients, leveraging innovative techniques to maximize efficacy while minimizing adverse effects. This article explores the latest advancements in chemotherapy innovations, focusing on how personalized approaches are revolutionizing cancer treatment.