Journal of Clinical Case Reports

Heart failure affects more than 40 million people globally in a single year and is expected to increase in the coming time. In patients, who have associated co-morbidities are more likely to develop left ventricular dysfunction and subsequently heart failure. Left ventricular dysfunction increases cardiovascular mortality and morbidity in end stage renal disease patients on hemodialysis. Peritoneal dialysis has emerged as an alternative mode of renal replacement therapy for end stage renal disease patients. However the prevalence of left ventricular dysfunction in end stage renal disease patients is scarcely known. A 33.33% prevalence of left ventricular dysfunction has been observed in our study.

Coronary sinus ostial atresia is a rare encounter in the intervention laboratory and is often linked with several congenital cardiac anomalies such as persistent left superior vena cava among others. Over the course of Cardiac Resynchronization Therapy (CRT), our case had the coronary sinus directly communicating with the superior vena cava through an anomalous bridging vein in the absence of a persistent left superior vena cava, along with an atretic right atrial ostium. Also, of interest was the minimal amount of technical challenge offered by such an anomaly for CRT lead implantation provided an otherwise favorable coronary anatomy.

Background: It is recognized in the medical community the world over that intervertebral disc tissue degenerates over the course of life and cannot be regenerated endogenously. But as all living tissue, intervertebral disc cells should be able to absorb and metabolize nutrients and replicate, thereby enabling regeneration. By this logic, disc regeneration should be possible by improving nutrient absorption, which is dependent on correct biomechanics. The role of the autonomic nervous system is critical in understanding function of tissue, including intervertebral discs.

Case report: In this case study, a man 45-year of age with disc degeneration of the lower lumbar spine between L5 and S1 and pain during exercise was treated with a series of full spine chiropractic adjustments in order to correct biomechanics and improve nutrient absorption of the intervertebral discs. This resulted in the growth of the degenerated disc, which increased the lateral angle between L5 and S1 by 80% coinciding with freedom of pain, free range of motion and an improvement of autonomic balance. This was documented by full spine X-rays and a pre- and post-scan of the autonomic nervous system.

Conclusion: This study shows that growth of intervertebral disc tissue is possible without the use of medication, surgery or cell transplantation and should be the beginning of rethinking functional physiology and the importance of translational medicine.

Castleman Disease (CD) is an uncommon lymphoid hyperplasia occurring in the mediastinal lymph nodes, and less frequently in the neck lymph nodes. Several factors, likewise Multiple Sclerosis (MS), are reported to be involved in the mechanism of each of the diseases.