Journal of Spine

Usefulness of Computed Tomography (CT)-Guided Biopsy for Etiological Diagnosis of Vertebral Destruction Syndrome

Abstract

Alejandro Antonio Reyes-Sánchez, Claudia Obil-Chavarría, Guadalupe Sánchez-Bringas and Eleazar Lara-Padilla

Purpose: It has been observed to biopsy directed by computerized axial tomography as axis for the diagnosis of vertebral destruction syndrome VDS. Evaluate the usefulness of CT-guided biopsy to determine the etiology of VDS.

Method: Cross-sectional, analytical study of diagnostic tests, which took place in individuals of any age who were admitted with a diagnosis of syndrome of vertebral destruction, attended for the first time. The sample size consisted of 91 patients; computerized axial tomography-guided biopsy was performed. We compared the results of the biopsy between two pathologists from different institution.

Results: Definitive histological findings were grouped into 7 categories: osteomyelitis (15.3%), tumors (38.46%), metastasis (37.36%), normal tissue (3.29%), inflammation (2.19%), and showing inadequate 0%, Pott’s disease (3.29%). According to the values of Z obtained by test of 2 proportions, with a n = 91, p = 0.05, the critical value of Z, two-tailed, was from 1.966 (±); they found no significant difference between the results reported by 2 different pathology services in vertebral biopsy guided by CT in Vertebral destruction syndrome; determining that this part of the process is a counselor on a 96.7% and final by 79%.

Conclusion: Percutaneous biopsy guided by tomography is an essential tool for the diagnosis of the syndrome of vertebral destruction approach and the ability to get diagnostics in the 96.7% indicates that it is a fundamental in the study of this syndrome.

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