Journal of Cytology & Histology

ISSN: 2157-7099

Open Access

Are Demilunes in Mixed Salivary Glands Real or Fixation Artifacts? A Critique


Bernard Tandler

Demilunes have historically been considered to be integral components of the secretory tree of mixed salivary glands. Based on preservation of rat sublingual glands by rapid freezing and freeze-substitution fixation, Yamashina et al. have advanced the notion that serous demilunes are artifactual products of chemical fixation, that swollen mucous cells cause a relocation of serous cells to the endpiece periphery. This concept has been uncritically accepted by several authors of histology textbooks. This note presents a compendium of observations and unanswered questions that render this proposition untenable.


Share this article

50+ Million Readerbase

Recommended Conferences

Journal Highlights

Google Scholar citation report
Citations: 1837

Journal of Cytology & Histology received 1837 citations as per Google Scholar report

Journal of Cytology & Histology peer review process verified at publons

Indexed In

Recommended Conferences
arrow_upward arrow_upward