Egypt						                            
                            
						
 Research Article
												Role of Mucosal Colonic Biopsy in Patients with Chronic Unexplained Diarrhoea who their Colonoscopy is Normal 						
Author(s): Dalia M Badary and Mohamed Z HafezDalia M Badary and Mohamed Z Hafez             
						
												
				 Objective: We sought to determine the importance of histopathological assessment in patients with chronic diarrhoea who had macroscopically normal colonic endoscopies.
Methods: Of 300 consecutive patients undergoing colonoscopy by one endoscopist during a five year period, biopsies were taken in 200 cases of unexplained diarrhoea of at least 6 weeks and their colorectal mucosa appeared macroscopically normal. All biopsies were reviewed by one pathologist.
Results: Of the 200 patients enrolled, 36 (18%) cases were classified as unremarkable histopathological diagnosis and 164 (82%) cases showed histopathological changes: 121 (73.78%) non-specific inflammation, 19 (11.58%) ulcerative colitis, 11 (6.7%) collagenous colitis, 7 (4.26%) lymphocytic colitis, and 6 (3.65%) bilharzial colitis.
Conclusion:.. Read More»
				  
												DOI:
												 10.4172/2168-9547.1000185 
																	  
Molecular Biology: Open Access received 607 citations as per Google Scholar report