Journal of Clinical Case Reports

The Challenging Diagnosis of Myocarditis Induced by Immune Checkpoint Inhibitors: A Case Report and Review of the Literature

Abstract

Amina Ridoine*, Marielle Morissens and Jose Castro Rodriguez

Immune Checkpoint Inhibitors induced Myocarditis is a serious adverse event. The clinical manifestation can be quite variable and the classic features of myocarditis are not always found. Although challenging, the diagnosis remains necessary in this potentially life-threatening complication. We present the case of a patient treated with nivolumab who developed a late immune checkpoint inhibitor induced myocarditis, without positive diagnostic findings in cardiac magnetic resonance imaging. Early initiation of corticosteroid therapy resulted in good outcome.