Journal of Clinical Case Reports

ISSN: 2165-7920

Open Access

Sjogren s Syndrome Involving the Central Nervous System Lesions as the First Performers: A Case Report and Literature Review


Xue-Wu Liu, Shan Qiao, Tao Han, Wen-Na Li, Ming-zhu Meng, Sheng-jun Wang, Xiu-he Zhao and Zhao-Fu Chi

Sjogren’s syndrome is primarily a chronic systemic autoimmune disease that involves many systems. However,
Sjogren’s syndrome involving the central nervous system lesions, particularly in the central nervous system
symptoms as the first performers is uncommon. In this report, we present a 33-year-old woman having PSs with
CNS involvement, whose first symptoms presented progressive weakness on the left leg, 2 years later the left upper
limb appeared the same symptoms, being diagnosed with Sjogren’s syndrome. To give methylprednisolone pulse
therapy, combined with cyclophosphamide and anetholtrithione treatment, her condition improved. After six months’
following-up, no recurrence.


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