Journal of Clinical Case Reports

A Case of Encephalitis Secondary to NMDA Receptor Antibody with Concurrent Striational Antibodies and Thymic Hyperplasia

Abstract

Gabriel D McCoy, Mark Call and Mansi Patel

The number of paraneoplastic encephalitis cases has been gradually rising. The most common one being anti- N -methyl-D-aspartate (NMDAR) encephalitis (over 120 cases reported in literature) [1]. Various other synaptic antibodies have also been associated with autoimmune encephalitis. These include: anti-leucine-rich glioma- inactivated protein (LGI1), anti-α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid (AMPAR), anti-gamma-aminobutyric acid (GABA-B) receptor, and anti-contactin-associated protein 2 (CASPR-2).