The heart pumps blood to maintain circulation and ensure the delivery of oxygenated blood to all the organs of the body. Mechanics play a critical role in governing and regulating heart function under both normal and pathological conditions. Biological processes and mechanical stress are coupled together in regulating myocyte function and extracellular matrix structure thus controlling heart function. Here we offer a brief introduction to the biomechanics of left ventricular function and then summarize recent progress in the study of the effects of mechanical stress on ventricular wall remodeling and cardiac function as well as the effects of wall mechanical properties on cardiac function in normal and dysfunctional hearts. Various mechanical models to determine wall stress and cardiac function in normal and diseased hearts with both systolic and diastolic dysfunction are discussed. The results of these studies have enhanced our understanding of the biomechanical mechanism in the development and remodeling of normal and dysfunctional hearts. Biomechanics provide a tool to understand the mechanism of left ventricular remodeling in diastolic and systolic dysfunction and guidance in designing and developing new treatments.
Research Article: Cardiovascular Diseases & Diagnosis
Research Article: Cardiovascular Diseases & Diagnosis
Case Report: Cardiovascular Diseases & Diagnosis
Case Report: Cardiovascular Diseases & Diagnosis
Research Article: Cardiovascular Diseases & Diagnosis
Research Article: Cardiovascular Diseases & Diagnosis
Research Article: Cardiovascular Diseases & Diagnosis
Research Article: Cardiovascular Diseases & Diagnosis
Case Report: Cardiovascular Diseases & Diagnosis
Case Report: Cardiovascular Diseases & Diagnosis
Posters & Accepted Abstracts: Cancer Science & Therapy
Posters & Accepted Abstracts: Cancer Science & Therapy
Scientific Tracks Abstracts: Cancer Science & Therapy
Scientific Tracks Abstracts: Cancer Science & Therapy
Accepted Abstracts: Journal of Forensic Research
Accepted Abstracts: Journal of Forensic Research
ScientificTracks: Cancer Science & Therapy
ScientificTracks: Cancer Science & Therapy
Posters & Accepted Abstracts: Journal of Trauma & Treatment
Posters & Accepted Abstracts: Journal of Trauma & Treatment
Cardiovascular Diseases & Diagnosis received 427 citations as per Google Scholar report