Indiana						                            
                            
						
 Research Article
												Experimental Study on Parkinson Disease Model of Rats 						
Author(s): Cao Fei, Sun Sheng-Gang, Cao Xue-Bing, Wang Tao, Cheng Ji-Xiang, Mei Yuan-Wu, Tong E-Tang and Luo FangCao Fei, Sun Sheng-Gang, Cao Xue-Bing, Wang Tao, Cheng Ji-Xiang, Mei Yuan-Wu, Tong E-Tang and Luo Fang             
						
												
				 Objective: To observe the characteristics of praxiology of Parkinson disease (PD) rats. Methods: At 1d, 7d, 14d after PD rats’ model were successful; we observed the markers of rotational behavior of Parkinson disease (PD) rats. For example: start time, continuous time, maximum turning, etc.
Results: From 1d to 14d, PD rats, start time of the rotational behavior elongated gradually, continuous time shortened by degrees, maximum rotational speed and the number of the rotational behavior were invariable.
Conclusions: Improved method of PD is scientific, reliable, and simple. Substantial nigral pathology of PD rats makes the foundation of the rotational behavior. The injury of substantial nigral can be reflected by maximum rotational speed and the number of the rotational behavior of PD rats.
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												DOI:
												 10.4172/2329-6895.1000127 
																	  
Neurological Disorders received 1343 citations as per Google Scholar report