Journal of Bioanalysis & Biomedicine

Sadayoshi Taguchi

Publications

• Research Article
  Spaceflight and Biohistochemical Alterations of Antigravity Soleus Muscle in Spontaneously Hypertensive Rats (SHR) to Dietary Low and High-Calcium Intake
  Author(s): Sadayoshi Taguchi, Shigehiko Ogoh, Takeshi Hashimoto, Sakiya Yamasaki, Hiroshi Okamoto, Yukio Yamori, Daniel C Hatton and David A McCarronSadayoshi Taguchi, Shigehiko Ogoh, Takeshi Hashimoto, Sakiya Yamasaki, Hiroshi Okamoto, Yukio Yamori, Daniel C Hatton and David A McCarron
  
  Dietary calcium supplementation has been to alter calcium metabolism and prevent hypertension in spontaneously hypertensive rats (SHR). Likewise, microgravity alters calcium metabolism. It is possible that the alteration of calcium metabolism caused by different levels of dietary calcium or microgravity change skeletal muscle properties. The purpose of this investigation was to determine whether spaceflight and/or dietary calcium causes alteration of properties in skeletal muscle from SHR. Nine-week-old male SHR, fed either high- (2.0%, HCa) or low-calcium (0.2%, LCa) diets, were flown on an 18-day shuttle flight. They were assigned to four groups (n=7/group): control (ground-based) with LCa or HCa, spaceflight with LCa, or HCa. After the spaceflight, the soleus muscle was dissected and analyzed histochemically and biochemically. Spaceflight caused a slow-to-fast f.. Read More»
  DOI: 10.4172/1948-593X.1000151

  Abstract PDF