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Short Communication
Acid-sensing Ion Channel 2 Expression in the Epithelial Cells of Rat Cerebral Ventricle and Choroid Plexus
Author(s): Shin Kikuchi, Takafumi Ninomiya, Tomoyuki Kawamata and Haruyuki TatsumiShin Kikuchi, Takafumi Ninomiya, Tomoyuki Kawamata and Haruyuki Tatsumi
Acid-sensing ion channel 2 (ASIC2) works as a proton-gated ion channel. Our previous report showed that ASIC2 was expressed in ciliated and stereociliated cells. In the central nervous system, ASIC2 was detected in neurons. However, ciliated ependymal cells also expressed ASIC2. In addition to ependymal cells in the cerebral ventricle, epithelial cells of the choroid plexus expressed ASIC2. We clarified that ASIC2 localized at the cilia membrane in ciliated ependymal cells and at the epithelial cell body in the choroid plexus, irrespective of ciliation. The role of ASIC2 in the ependymal cells remains to be clarified... Read More»
DOI:
10.4172/2157-7099.1000310
Journal of Cytology & Histology received 1837 citations as per Google Scholar report
