Germany
Case Report
Metastatic Liposarcoma: A Case of Partial Remission with Eribulin in Late Treatment Lines
Author(s): Viktor Grunwald and Philipp IvanyiViktor Grunwald and Philipp Ivanyi
Liposarcoma, a type of soft tissue sarcoma, represents a therapeutic challenge, in particular in the metastatic setting. This case describes a patient with retroperitoneal liposarcoma that was first treated by surgery and, upon manifestation of metastatic disease, with a series of chemotherapy regimens comprising doxorubicin (line 1), doxorubicin plus ifosfamide (line 2), trabectedin (lines 3 and 4) and dacarbazine (line 5). While transient partial remission was achieved in the first three lines, rapid disease progression was observed in subsequent therapies. After failure of the previous chemotherapy regimens, eribulin was administered (line 6), and partial remission was achieved within five months. However, the occurrence of grade 3 polyneuropathy led to temporary discontinuation of therapy. Overall, metastatic liposarcoma was controlled for twelve months with eribulin treatment in .. Read More»
DOI:
10.4172/2165-7920.10001109
Journal of Clinical Case Reports received 1295 citations as per Google Scholar report