Journal of Cytology & Histology

Jan Evangelista Jirasek

Publications

• Case Report
  HPV Typization in Vaccinated Women with Cervical Lesions
  Author(s): Jitka Kobikova, Jan Evangelista Jirasek, Marcela Drazdakova, Miloslav Janousek, Marie Strunova, Vaclav Hejda and Jaroslav HoracekJitka Kobikova, Jan Evangelista Jirasek, Marcela Drazdakova, Miloslav Janousek, Marie Strunova, Vaclav Hejda and Jaroslav Horacek
  
  Background and objective: 24 patients, all of them vaccinated in postpubertal period, on their own descision, all of them had abnormal PAP tests. In all of them an expert colposcopy was performed, in all of them a low and high grade cervical lesion was detected. HPV genotypization, punch biopsy of the lesion folowed by histology and immunohistochemical staining of p16 INK4a were performed. Study design: Our study concerns 24 patients suffering of cervical lessions. The age of these patients was 20- 34 years. 20 of them were vaccinated by Silgard and 4 of them by Cervarix. Results: Two patients were hrHPV negative, in 21 patients the cervical lesions were infected with different HPV combinations, only in one woman single hrHPV type 52 was present. The frequent hrHPV types occurence was: 52/11x/, 39/11x/, 31/9x/, 45/6x/,.. Read More»
  DOI: 10.4172/2157-7099.1000223

  Abstract PDF