College of Pharmacy & Health Sciences,
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Tanzania
Research Article
The Economic Impact of Changing Levothyroxine Formulations in Difficult-to-Treat Hypothyroid Patients: An Evidence-Based Model
Author(s): Riad Elmor, Walter Sandulli and Charles A. CarterRiad Elmor, Walter Sandulli and Charles A. Carter
Objective: To determine the budget impact of incorporating levothyroxine gel caps in the treatment plan of patients diagnosed with hypothyroidism who experience multiple levothyroxine dose or formulation changes annually due to inadequate efficacy or tolerability.
Methods: Cost estimates of levothyroxine formulations were obtained. Estimated utilization patterns and costs of physician services, laboratory tests, ancillary healthcare services, and lost productivity were quantified based on published literature and government/public sources. The patient population was based on epidemiology reports and estimates from the American Association of Clinical Endocrinology and the American Thyroid Association. All calculations of economic outcomes were determined using a budget impact model constructed in a MS Excel platform.
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DOI:
10.4172/2472-1042.1000113
Pharmacoeconomics: Open Access received 106 citations as per Google Scholar report