Journal of Oncology Medicine & Practice

Viveka Nand Yadav

Viveka Nand Yadav
Department of Neurosurgery
University of Michigan, USA

Biography

Dr. Viveka Nand Yadav was among the top 10% (contestant for Shyama prasad mukherjee award) of the candidates, who qualified for the Junior Research Fellowship (for PhD studies) in the National Eligibility Test conducted by Council of Scientific and Industrial Research (CSIR), Govt. of India in Dec 2005.Postdoctoral Fellowship, Department of Neurosurgery at the University of Michigan, USA, 2013 –present. Recipient of Senior Research Fellowship from Department of Biotechnology, Government of India (2008-2011). He was among the top 10% (contestant for Shyama prasad mukherjee award) of the candidates, who qualified for the Junior Research Fellowship (for PhD studies) in the National Eligibility Test conducted by Council of Scientific and Industrial Research (CSIR), Govt. of India in Dec 2005. Current Research on Glioblastoma (GBM) is the most lethal of the human cancers.He is Ad hoc reviewer for many reputed medical journals. He has many Poster Presentation in conferences entitled: In vivo and In vitro studies show that brain derived endothelial cells stimulate migration of human, mouse and rat glioma cells at 21st Annual Scientific Meeting of the Society for Neuro-Oncology, 2016, Scottsdale, Arizona, USA, Genetic down regulation of CXCR4 in glioma cells reduces invasion and tumor progression, and sensitizes tumors to radiation at the 4th Annual Cancer Biology Graduate Program Retreat 2016, University of Michigan, Ann Arbor, MI, In vivo and In vitro studies show that brain derived endothelial cells stimulate migration of human, mouse and rat glioma cells at 20th Annual Scientific Meeting of the Society for Neuro-Oncology, 2015,San Antonio, USA, In vivo and In vitro studies depict that brain derived endothelial stimulate migration of different Human, Mouse and Rat glioma cell lines at the 3rd Annual Cancer Biology Graduate Program Retreat 2015, at the Kellogg Biological Station, Battle Creeck, MI

Research Interest

Has expertise in Designing and cloning of sgRNA and executing gene knock down using CRISPR/Cas-9 system. Epifluorescence and Confocal Fluorescence Microscopy, paraffin/OCT embedding and cryosectioning of mouse brain, human and mouse brain perfusion Immunocytochemistry, Immunohistochemistry, H&E, Fluorescence staining of mouse and human brains. Stereotactic mouse brain surgery for tumor implantation using sleeping beauty technology. Generation of GBM cell lines from human brain tissue samples. Molecular cloning, Lentiviral vector construction, transfection and transduction. Protein expression and purification, western blotting, ELISA Mouse handling for in vivo experiments including brain surgeries and drug treatments. As part of phase I clinical trial of Adenoviral mediated (Ad-TK+Ad-Flt3L) gene therapy for high-grade glioma at University of Michigan (NCT01811992) I am monitering stability of adenovirus (Ad-TK and Ad-Flt3L) by the restriction analysis as well as functionality by measuring TK and Flit3L expression in patients.